De Novo Assembly

De novo and reference-based genome assemblies.


Gain a deep understanding of both: de novo and reference-based genome assemblies.
Potential sources of error can be addressed up front by measuring assembly quality and generation of reliable statistics.

Benefit from our strong connections to world-leading researchers that allow us to develop cutting edge tools and pipelines for assemblies of all genome sizes.


  • Chromosome level assemblies: Generation of genome assemblies for even large polyploid genomes.
  • Polyploid genomes: Assembling of large, polyploid genomes (so far, up to 22 Gbp in size).
  • Genetic variance studies, marker development, and pre-breeding: Get additional resources to apply your de novo assembly results.

Client project: De novo assembly of two indica elite rice lines

We performed a de novo assembly of two indica elite rice lines using Illumina and PacBio data. We constructed a genetic map using 2000 F2 individuals to build pseudochromosome level assemblies with > 95% of the scaffolds in chromosomes and > 99% gene space covered.

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Tübingen, Germany

Computomics is based in the university town of Tübingen, situated in the Southwest of Germany, but serves clients all over the world. We also have offices in Davis, California and Madison, Wisconsin.

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Computomics GmbH
Christophstr. 32
72072 Tübingen

Phone: +49 7071 568 3995