Explore Tailored Microbiome Solutions for Your Industry.
Computomics provides Metagenomics Data Analysis Solutions for bacterial, archaeal, fungal and viral community profiling that enable you to simultaneously identify thousands of species, millions of genes, and diverse biochemical pathways relevant to agriculture, medicine, and the environment.
From farm to fork and beyond, we unlock the potential of microbes for a healthier future.
Explore Tailored Microbiome Solutions for
Computomics offers exceptional support in understanding the soil, plant, and seed microbiome and in providing insights into biotic and abiotic stressors. We collaborate to explore plant genotype-based recruitment of beneficial microbes, reducing the need for chemical fertilizers and pesticides through tailored biological treatments.
Our metagenomics platform applies machine learning-driven feature importance analysis, speeding up agricultural management decisions to help you achieve sustainability goals and enhance climate-friendly solutions.
Benefits:
While the increasing world population demands advanced and secure food production, climate change is causing significant harvest losses. Beyond conventional methods like breeding and fertilization, innovative approaches target the native microbial community on agricultural plants.
We help you understand natural microbial diversity and identify key microbial players that enhance resistance to stressors such as drought, flooding, and salinity. We also identify risk factors for pathogen susceptibility, including food-borne pathogens.
Together, we will build your microbial knowledge base to develop new strategies for bionutrition, bioprotection, and an improved microbial carbon use efficiency (Carbon Capturing and Sequestration).
More information: See our machine learning-driven feature importance analysis for the identification of marker taxa, published in BMC Environmental Microbiome: "Interpretable machine learning decodes soil microbiome’s response to drought stress".
Computomics leverages microbiome analyses to achieve a safer, quality-enhanced, and more sustainable food production, all while supporting the interconnection to human, animal, and environmental health. Besides pathogens detection, we support you in mitigating spoilage, optimizing microbial food processing steps and reusing food waste in a circular economy.
Our microbiome analysis tool facilitates monitoring of microbial communities and their metabolic pathways from the early production towards retail and storage. Centralized data collection from all production sites fosters decision support towards preventive or immediate actions while standardizing report strategies for food authorities.
Benefits:
Microbiome analysis provides outstanding features for food contamination detection or metabolic reconstruction of food processing strains. Yet still well-established culture-based approaches (e.g. cultivation, qPCR) dominate the food landscape.
Use our platform to combine both culture-dependent and independent analysis results. Easily trace microbial genotypes continuously, in particular of pathogens, like of the ESKAPEE group, and detect hazard outbreaks at an early stage. Similarly, analyze antibiotic resistance genes and their spread to achieve highest food security and to comply with food regulations.
We also assist you in the microbial assessment of novel technologies in food preservation (e.g. packaging), processing (e.g. textures, flavours) and consumer health (e.g. probiotics of the LAB group).
"Microorganisms - the good, the bad, the ugly." Listen to our podcast with Kalliopi (Kelly) Rantsiou, professor at the University of Turin, on the SAFFI - Safe Food for Infants - project. This European-funded project evaluates how pathogenic microorganisms may contaminate food for infants, and how we can understand ways of controlling these microorganisms.
Whether for human or animal health, microbiome analysis plays a crucial role in disease prevention, nutrition (e.g. diets), growth (feed efficiency), and overall well-being (gut-brain-axis).
Our metagenomics pipeline applies feature importance analysis to give hint for microbial perturbations and its causative agent. Thus, we promote product testing not only for the pharmaceutical and cosmeceutical industries, but also for novel nutritional concepts.
Get actionable insights into biofilms, phageomes, resistomes, and metabolomes and develop impactful strategies against cancer!
Benefits:
Diets profoundly shape gut microbiome composition and are often applied to fight dysbiosis. Such dysbiotic microbiomes may promote low-grade inflammation and contribute to obesity or metabolic disorders. A deep understanding of the effect of a healthy nutrition such as “high protein, low carbon” (HPLC) compared to “medium protein, medium carbon” (MPMC) requires the consideration of the consumer’s prior health state to treat respective symptoms in a personalized manner.
Besides explaining microbial shifts, we provide a deeper understanding in the accompanying pathogenicity and respective metabolome for an unparalleled health and risk assessment.
Advanced biotechnological approaches are essential for achieving sustainability and global health. Microbial-based techniques are gaining in importance for degradation of undesired substances (e.g. toxins, heavy metals), for biomass conversion into value-added compounds (e.g. biofuel, bioplastics), or for studying novel enzymes and metabolic cycles (e.g. of carbon- and nitrogen-derivates) to alleviate climate change.
Our Metagenomics long read solutions address theses needs through whole microbial genome assembly from microbiomes (MAGs), including biosynthetic gene cluster (BGCs) detection and metabolic reconstruction. Furthermore, we apply a comparative genomics pipeline to discover novel microbial strains and gene variants.
Benefits:
"Variability in n-caprylate and n-caproate producing microbiomes in reactors with in-line product extraction": Learn more about the n-caprylate production from ethanol and acetate via the RBOX pathway in open-culture reactors, a value-added compound for industrial and agricultural applications.
Electrogenic bacteria residing on anodes in microbial fuel cells (MFCs) produce bioelectricity by degrading organic compounds. Respective substrates can be administered through waste water plants (e.g. municipal or brewery wastewater, cattle manure). Another interesting example are sediment MFCs, which make use of the naturally occurring redox gradient among the sediment-water interface.
Other applications for MFCs are biosensors in waste water monitoring, environmental pollutants detection and removal (e.g. desalination cells) or carbon sequestration (microbial carbon capture cells, MCCCs). Together with us, explore the potential of microbial applications for your processing technologies, or take the opportunity to analyze and monitor your existing cultures!
