De Novo Assembly

De novo and reference-based genome assemblies.


Gain a deep understanding of both: de novo and reference-based genome assemblies.
Potential sources of error can be addressed up front by measuring assembly quality and generation of reliable statistics.

Benefit from our strong connections to world-leading researchers that allow us to develop cutting edge tools and pipelines for assemblies of all genome sizes.


  • Chromosome level assemblies: Generation of genome assemblies for even large polyploid genomes.
  • Polyploid genomes: Assembling of large, polyploid genomes (so far, up to 22 Gbp in size).
  • Genetic variance studies, marker development, and pre-breeding: Get additional resources to apply your de novo assembly results.
ASSEMBLY reference_based_TO_reference Kopie

Client project: De novo assembly of two indica elite rice lines

We performed a de novo assembly of two indica elite rice lines using Illumina and PacBio data. We constructed a genetic map using 2000 F2 individuals to build pseudochromosome level assemblies with > 95% of the scaffolds in chromosomes and > 99% gene space covered.

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Tübingen, Germany

Computomics is based in the university town of Tübingen, situated in the Southwest of Germany, from where we serve clients all over the world.

We also have a presence in Madison, Wisconsin and in the Washington, DC area.

Computomics GmbH
Eisenbahnstr. 1
72072 Tübingen

Phone +49 7071 568 3995